Prof. Levanon Erez – Genome-wide quantification of ADAR adenosine-to-inosine RNA editing activity

Prof. Erez Levanon

Abstract Adenosine-to-inosine (A-to-I) RNA editing by the adenosine deaminase that acts on RNA (ADAR) enzymes is a common RNA modification, preventing false activation of the innate immune system by endogenous double-stranded RNAs. Methods for quantification of ADAR activity are sought after, due to an increasing interest in the role of ADARs in cancer and autoimmune…

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