Abstract Objectives To resolve the controversy regarding the presence of a microbiota in the placenta. Design Classical and molecular microbiological study. Setting All samples were collected during caesarean section. Population A total of 28 human placentas and six murine placentas. Methods All 28 human placentas were checked for 16S rRNA gene amplification products. Three locations…

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Highlights Bifidobacterium abundance increases in the gut during pregnancy in women and mice Progesterone supplementation alters gut microbial composition in mice and in vitro Progesterone supplementation increases Bifidobacterium abundance in mice and in vitro We suggest that progesterone promotes Bifidobacterium growth during late pregnancy Summary Gestation is accompanied by alterations in the microbial repertoire; however, the mechanisms driving these changes are unknown. Here, we…

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