Biology and medicine are undergoing a tremendous revolution where the use of advanced technologies, sophisticated bioinformatics and big data, revealing immediate impact on translation to medicine including disease diagnosis, treatment and outcome. Thus the main objective of this proposal that combines clinical and scientific skills is to extend our knowledge on pathways controlling human immunity in early life, to increase the number of primary immunodeficiency diseases to be diagnosed early in life, understand new disease pathomechanisms and to develop a novel and personalized gene-based treatment.
Prof. Raz Somech, Sheba Medical Center
Dr. Ayal Hendel, Bar Ilan University
Dr. Yu Nee Lee, Sheba Medical Center