Dr. Ayal Hendel

Abstract The prototypical genetic autoimmune disease is immune dysregulation polyendocrinopathy enteropathy X-linked (IPEX) syndrome, a severe pediatric disease with limited treatment options. IPEX syndrome is caused by mutations in the forkhead box protein 3 (FOXP3) gene, which plays a critical role in immune regulation. As a monogenic disease, IPEX is an ideal candidate for a…

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Background: The experience of an acute coronary event (ACE), including early care and evaluation, can be a distressing and traumatic experience for patients and their romantic partners, who also act as caregivers. We hypothesized that, among partners who were present during the ACE, those who were also present during (1) transportation to the hospital and (2)…

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Abstract Adult neurogenesis is a complex physiological process, which plays a central role in maintaining cognitive functions, and consists of progenitor cell proliferation, newborn cell migration, and cell maturation. Adult neurogenesis is susceptible to alterations under various physiological and pathological conditions. A substantial decay of neurogenesis has been documented in Alzheimer’s disease (AD) patients and…

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Attachment insecurity hinders cardiac patients’ ability to receive partners’ care: A longitudinal dyadic study Show all authorsSivan George-Levi, Shira Peleg, Noa Vilchinsky, …First Published February 3, 2020 Research Articlehttps://doi.org/10.1177/0265407519900998 Article information  Abstract Objectives: The fact that spousal support is not always beneficial for the recipient continues to intrigue researchers in the dyadic support field. One possible explanation for this phenomenon…

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Abstract Introduction Epidural analgesia (EA) is an established option for efficient intrapartum analgesia. Meta‐analyses have shown that EA differentially affects the first stage of labor but prolongs the second. The question of EA timing remains open. We aimed to investigate whether EA prolongs delivery in total and whether the EA administration timing vis‐à‐vis cervical dilation…

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