Dr. Ayal Hendel – Primary immunodeficiencies – from early diagnosis and gene discovery to personalized therapy
Biology and medicine are undergoing a tremendous revolution where the use of advanced technologies, sophisticated bioinformatics and big data, revealing immediate impact on translation to medicine including disease diagnosis, treatment and outcome. Thus the main objective of this proposal that combines clinical and scientific skills is to extend our knowledge on pathways controlling human immunity…Read More
Nucleic Acids Research, 2019 1–15 doi: 10.1093/nar/gkz477 Pseudouridines on Trypanosoma brucei spliceosomal small nuclear RNAs and their implication for RNA and protein interactions K. Shanmugha Rajan1, Tirza Doniger 1, Smadar Cohen-Chalamish1, Dana Chen1, Oz Semo1, Saurav Aryal1, Efrat Glick Saar2, Vaibhav Chikne1, Doron Gerber 1, Ron Unger1, Christian Tschudi3 and Shulamit Michaeli 1,* 1The Mina…Read More
Dr. Meital Gal-Tanamy -Dysregulation of the cohesin subunit RAD21 by Hepatitis C virus mediates host–virus interactions
Abstract Hepatitis C virus (HCV) infection is the leading cause of chronic hepatitis, which often results in liver fibrosis, cirrhosis and hepatocellular carcinoma (HCC). HCV possesses an RNA genome and its replication is confined to the cytoplasm. Yet, infection with HCV leads to global changes in gene expression, and chromosomal instability (CIN) in the host…Read More
Familial Kaposi’s sarcoma and genetic whole exome analysis Background: Kaposi’s sarcoma (KS) is a rare malignancy most commonly appearing in HIV carriers. In addition to HIV carriers, there are rare families with genetic predisposition for KS, some are Jewish descent from Morocco. Professor Moshe Schaffer identified a few such families in his service as oncologist…Read More
The first grant of the Dangoor Center for Personalized Medicine has been awarded to a project using innovative epigenetic methods in order to enhance diagnosis and treatment of patients with acute coronary disease. Cardiovascular diseases are defined by the patient’s loss of flexibility in his or her blood vessels or his or her obstructed and…Read More
Welcome to The Dangoor Centre for Personalized Medicine
Welcome to The Dangoor Centre for Personalized Medicine located at Bar-Ilan University, which is spearheading the research and application of personalized medicine through:
Having been operating for more than a year now, the Centre’s mission is to become a gateway to the healthcare community.
Our website focuses on promoting awareness, understanding, and application of Personalized Medicine by healthcare professionals. Our goal is to offer accurate and relevant data that serves as a platform for forging relationships between researchers and physicians, and promoting collaboration.
The Dangoor Centre’s website is not only a portal for information on Personalized Medicine, but also an interactive platform through which members can access Research Articles and Case Studies.
Most important of all is the fact that physicians can submit a request for a Case Review and receive guidance in applying PM from Bar-Ilan University researchers.
The site also serves as a database of applied research and activities related to personalized medicine.
What is Personalized Medicine?
Personalized Medicine is the selection of a course of treatment based on an analysis of the patient’s genetic and epigenetic history, and the genetic footprint of the disease that he/she is fighting. Often, patients are genetically predisposed to respond more favorably to one of several treatment options. Taking genetic data into consideration can often result in better treatment choice, and a better outcome.
It is an open secret that we cannot think about cure until and unless the medicine prescribed is a personalized one. Which is why we need The Dangoor Centre for Personalized Medicine, a platform that helps in enriching the knowledge of those related to the medical research field, be it the doctors, researchers or students. Contact us to learn more.